Chronic kidney disease (CKD) is increasing globally and also in India. The most common cause of CKD is diabetes. Other causes are hypertension, drugs (painkiller and contrast dye), cysts, infection, less blood supply (ischemia) to kidneys, and systemic disease. Though CKD in general is not curable, there are some kidney diseases for which specific treatments are available. Dr. Georgy K Nainan is Senior Consultant Nephrologist at PVSM Hospital and Lakeshore Hospital, Cochin clearly advise you how the vital organ can be protected.
Chronic kidney disease undergoes progression to reach the End-Stage Renal Disease (ESRD) through 5 stages. The first stage is a laboratory diagnosis. Microalbuminuria is the earliest sign of glomerular capillary dysfunction and is seen very much in diabetic patients. Microalbuminuria more than 30 mgs/day is significant. CKD is detected usually in the third stage, when the albumin is seen in the urine and 24-hour urine proteinuria exceeds 150 mg. In stage 4 and 5, serum creatinine and blood urea increase. God has given us two kidneys, and, unlike solid organs like heart, both kidneys work together as a collective function of 26 lakh nephrons (filtering units).
If you donate a kidney or remove a kidney or if 50 % of both kidneys are damaged due to any disease, creatinine does not increase. When creatinine increases over 1.4 mg % constantly, as seen in different laboratories, done by autoanalysers, it signifies 60% of nephronal dysfunction. Once CKD is detected, evaluation has to be done.
(Read the full article in the June Issue of Safety Messenger Magazine 2015)